According to the National Centre for Disaster Prevention (Cenapred), the volcano has had 34 exhalations and 5 explosions in the last 24 hours.
On Tuesday, volcanic debris was pelted 400 metres skywards, while a column of ash and smoke could be seen rising two kilometres high.
And 24 hours later, at 3.07am local time, the stratovolcano had had 215 minutes of exhalations and seismic movements.
The Volcano released emissions of gases, ash and incandescent fragments on the slopes of the volcano, while ash is still falling in Morelos and the Edomex from Tuesday's initial eruption.
Taking to twitter, the national coordinator of Civil Protection of the Ministry of the Interior, Luis Felipe Puente, announced the new report.
He also warned users to stay informed through official accounts: "Do not spread false information and follow the recommendations of @PcSegob."
The eruption reached two kilometres above the eruptive crater, dispersing ash towards the south west and sending tremors into the west of the area.
As a result of the increase in activity, ash was recorded falling in the municipalities of Tetela del Volcán, Yecapixtla, Tlalnepantla, Totolapan, Cuernavaca, Tepoztlan, Huitzilac and Tlayacapan in Morelos.
Ash and debris were also recorded in Amecameca, Acuautla, Ecatzingo, Ozumba and Tepetlixpa in the State of Mexico.
Seismic activity has returned to previous levels.
The 9,556km-high stratovolcano dominates the landscape in Central Mexico, lying about 69 kilometres (43 miles) from Mexico City.
Popocatepetl is classed as one of the 10-most populated volcanoes globally, according to the Natural History Museum.
The volcano has a population of about 30 million people living within a 70km radius of its summit.
Popocatepetl last erupted in February of this year. It was triggered by a massive 7.2 magnitude earthquake in southern Mexico.
Ash and gas shot into the air for more than 24 hours and the government’s Centro Nacional de Desastres (CENAPRED) urged people to stay well away.
Activity at Popocatepetl’s summit has increased since 1994 when people were sent scrambling during a violent eruption.